BDBM534569 WO2022086828, Example 305

SMILES Nc1nc2cc(ccn2n1)-c1ccc(C2CC2)c(C(=O)NCC(F)(F)[C@H](O)c2ccc(F)cc2)c1F

InChI Key InChIKey=KNIULYCUWOGHSI-JOCHJYFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534569   

TargetMixed lineage kinase domain-like protein(Homo sapiens)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534569(WO2022086828, Example 305)
Affinity DataIC50:  1.60nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed